Food intolerances and sensitivity reactions that are not due to an allergy:
Some foods, additives and chemicals are able to trigger immune reactions that are not due to allergies. The chemical mediators released by the immune system are capable of producing a variety of reactions and symptoms in the body. Avoiding foods that produce these reactions is supposed to resolve or at least significantly improve the symptoms of consuming those foods. The mediator release test (MRT) measures the release of chemical mediators from white blood cells and platelets in response to specific foods, additives or chemicals. Such chemical reactions presumably indicate sensitivity to these foods or additives.
Principles of commercially available mediator release tests (MRT):
Commercially available mediator release tests (MRT, Signet Diagnostic Corporation, http://www.nowleap.com ) is based on measuring the reaction in the blood of various immune mediator chemicals released in response to a food or chemical to which you have become sensitive or intolerant. The result is that when exposed to these foods or chemicals, blood cells release various chemicals that cause an alteration in the ratio of solids (cells) to liquids (serum) in the blood that can be measured. White blood cells and platelets shrink and the volume of the liquid increases. The degree of change can be measured and reported as mild or moderate to severe corresponding to the degree of sensitivity to that particular food, additive or chemical.
Test results of 150 foods and chemicals combined with diet and elimination advice:
A panel of 150 food and chemical products is available (123 foods and 27 chemicals). The foods or chemicals that produce abnormal reactions are summarized in the color tables provided together with a complete report containing a specific elimination diet plan based on the results integrated with several hours of personalized advice from a dietician.
Insurance coverage for food sensitivity and MRT intolerance tests:
Several insurance companies pay at least part of the cost of this test, however, since it is considered “offline” for most plans, patients are generally responsible for paying for the service. Some carriers consider the test “experimental” or not validated and therefore do not cover the test.
Conditions benefiting from MRT tests include migraine, IBS, fatigue and fibromyalgia:
Signet markets tests for several conditions based on limited published research combined with their extensive clinical experience and patient testimonials. They claim success in reducing or eliminating a myriad of symptoms or conditions. These include migraine, headache, autistic behavior, anxiety, depression, ADD, sinusitis and ears, nose and throat problems, irritable bowel syndrome, vomiting syndromes, celiac disease, chronic stomach pain, bladder problems, fibromyalgia , arthritis, eczema, urticaria and chronic fatigue syndrome.
The skeptical doctor and frustrated patients seek answers:
Initially, I was skeptical about the MRT. However, I started supporting him several months ago because many of my patients had ongoing symptoms or findings that suggested an ongoing food intolerance or sensitivity, but the tests available to us could not tell us which food or foods could be a problem. After reviewing the available research data, I linked MRT tests that had an adequate scientific basis to recommend it as an option to those interested and would consider making dietary changes based on the results.
Medical and food allergy patients find the MRT test useful and useful:
So far, my experience is that most of those who have been tested and have made dietary changes as a result have noticed a significant improvement in a variety of digestive and non-digestive symptoms. I have also noticed some very interesting patterns in people with other allergies. There appears to be a strong correlation with food-pollen cross reactions, more commonly known as oral allergic syndrome (OAS). I am following him systematically and I hope to formally report my observations in the future.
Previously available tests and dietary interventions fail to provide relief in some patients:
All of my patients who have decided to undergo MRT have already been tested for celiac disease and most have undergone food allergy tests and upper and lower endoscopy tests with biopsies. Everyone had already tried dietary interventions. Some have had tests that have confirmed one or more food allergies, celiac disease or gluten sensitivity or have mast cell enterocolitis; eosinophilic esophagitis, gastroenteritis or colitis; or lymphocytic enteritis. Although most had some improvement with dietary interventions based on their previous tests, many had ongoing symptoms with or without inconclusive or negative food allergy tests.
Get MRT tests and try an elimination diet:
I believe that MRT tests are a useful addition to the assessment and treatment of food intolerance. The test requires a doctor’s order. If your doctor isn’t familiar with the test, he can learn more about it http://www.nowleap.com . If your doctor won’t order the test, Signet can help you locate a doctor in your area or you can get the test as part of an online consultation. An elimination diet based on specific foods to which you are intolerant but not necessarily allergic can be the key to relief from a variety of symptoms and conditions. If you suspect a food intolerance, take the test today.